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Lack of PTX3 reduces striatal vascular density during the recovery phase after middle cerebral artery occlusion (MCAo). PECAM-1 staining in the striatum of wild-type (WT) and PTX3 knockout (KO) mice was quantified, showing that PTX3 KO mice have significantly less vasculature 14 days after MCAo (C). A similar trend, although not significant, is seen 48 h (A) or 6 days (B) post MCAo. Scale bars = 50 μm. Students t-test (n = 4) was used. **P <0.01. Error bars show SEM.
