Table 4.
Association of Number of Comorbidities With Cardiac Mechanics and Filling Pressures After Multivariable Adjustment (Model 2)*
| Dependent Variable | All Participants (n=2150) | Participants With Normal Left Ventricular Geometry (n= 1620) | ||
|---|---|---|---|---|
| β‐Coefficient (95% CI) | P Value | β‐Coefficient (95% CI) | P Value | |
| Global radial strain, % | −0.49 (−0.93, −0.06) | 0.02 | −0.52 (−1.02, −0.03) | 0.04 |
| Global circumferential strain, % | 0.02 (−0.16, 0.20) | 0.83 | 0.02 (−0.19, 0.22) | 0.87 |
| Global longitudinal strain, % | −0.32 (−0.44, −0.20) | <0.0001 | −0.29 (−0.42, −0.16) | <0.0001 |
| e' velocity, cm/s | −0.16 (−0.20, −0.11) | <0.0001 | −0.15 (−0.20, −0.10) | <0.0001 |
| E/e' ratio | 1.53 (0.96, 2.11) | <0.0001 | 1.45 (0.86, 2.02) | <0.0001 |
*
Adjusted for speckle‐tracking analyst, recruiting center, image quality, age, sex, race, left ventricular mass index, wall motion score, and ejection fraction.