Table 5.
Association of Number of Comorbidities With Cardiac Mechanics and Filling Pressures After Multivariable Adjustment—Excluding Participants With Prior Myocardial Infarction (Model 2)*
| Dependent Variable | All Participants (n=2019) | Participants With Normal Left Ventricular Geometry (n=1551) | ||
|---|---|---|---|---|
| β‐Coefficient (95% CI) | P Value | β‐Coefficient (95% CI) | P Value | |
| Global radial strain, % | −0.46 (−0.91, −0.00) | 0.048 | −0.46 (−0.96, 0.5) | 0.08 |
| Global circumferential strain, % | 0.04 (−0.15, 0.23) | 0.68 | 0.04 (−0.17, 0.25) | 0.69 |
| Global longitudinal strain, % | −0.33 (−0.45, −0.21) | <0.0001 | −0.29 (−0.43, −0.16) | <0.0001 |
| e' velocity, cm/s | −0.16 (−0.21, −0.12) | <0.0001 | −0.16 (−0.21, −0.11) | <0.001 |
| E/e' ratio | 1.60 (1.01, 2.18) | <0.0001 | 1.54 (0.95, 2.13) | <0.0001 |
*
Adjusted for speckle‐tracking analyst, recruiting center, image quality, age, sex, left ventricular mass index, wall motion score, and ejection fraction.