Table 6.
Association of Number of Comorbidities With Cardiac Mechanics and Filling Pressures After Multivariable Adjustment (Model 2)—Race‐Stratified Analyses*
| Dependent Variable | White Participants (n=1144) | African American Participants (n=998) | Race×Comorbidities Interaction P Value | ||
|---|---|---|---|---|---|
| β‐Coefficient (95% CI) | P Value | β‐Coefficient (95% CI) | P Value | ||
| Global radial strain, % | −0.23 (−0.86, 0.40) | 0.48 | −0.69 (−1.29, −0.09) | 0.025 | 0.44 |
| Global circumferential strain, % | 0.11 (−0.15, 0.36) | 0.43 | −0.12 (−0.38, 0.13) | 0.34 | 0.003 |
| Global longitudinal strain, % | −0.23 (−0.39, −0.07) | 0.005 | −0.39 (−0.57, −0.21) | <0.0001 | 0.026 |
| e' velocity, cm/s | −0.16 (−0.22, −0.10) | <0.0001 | −0.16 (−0.22, −0.09) | <0.0001 | 0.79 |
| E/e' ratio | 1.26 (0.61, 1.92) | <0.0001 | 1.95 (0.99, 2.91) | <0.0001 | <0.001 |
*
Adjusted for speckle‐tracking analyst, recruiting center, image quality, age, sex, left ventricular mass index, wall motion score, and ejection fraction.