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. 2014 May 16;3(3):e000732. doi: 10.1161/JAHA.113.000732

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© 2014 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Figure 1. — Association of Hp genotype with cardiovascular disease (CVD) risk by glycosylated hemoglobin (HbA_1c) level under progressive adjustment. No. of person‐years of follow‐up/cases was 9250/102 for subjects with HbA_1c<6.5% (4323/50 in the Hp 2‐2 and 4927/52 in the Hp 2‐1/1‐1 group) and 613/21 for subjects with HbA_1c≥6.5% (375/8 in the Hp 2‐2 and 238/13 in the Hp 2‐1/1‐1 group). Model 1 was adjusted for age and sex, model 2 additionally for current smoking, systolic blood pressure, LDL cholesterol, and HDL cholesterol, and model 3 additionally for metabolic equivalent hours, alternative healthy eating index, statin use, and body mass index. HbA_1c indicates glycosylated hemoglobin; HDL, high‐density lipoprotein cholesterol; LDL, low‐density lipoprotein cholesterol.