Table 4.
Hazard Ratios for Fatal and Nonfatal Cardiovascular Events in Relation to LV Diastolic Doppler Parameters Additionally Adjusted for LV Mass Index
| Predictor Variable | Cardiovascular Events (n=59) | Cardiac (n=40) | ||
|---|---|---|---|---|
| HR (95% CI) | P Value | HR (95% CI) | P Value | |
| Per SD decrease | ||||
| TDI e' | 2.35 (1.28 to 4.48) | 0.007 | 3.38 (1.52 to 7.28) | 0.002 |
| TDI a' | 1.11 (0.82 to 1.49) | 0.52 | 1.25 (0.86 to 1.79) | 0.24 |
| TDI e'/a' | 2.00 (0.79 to 3.72) | 0.17 | 1.80 (0.69 to 4.64) | 0.22 |
| Per SD increase | ||||
| E/A ratio | 0.76 (0.44 to 1.30) | 0.32 | 0.87 (0.45 to 1.66) | 0.66 |
| E/e' ratio | 1.11 (0.83 to 1.49) | 0.49 | 1.30 (0.92 to 1.83) | 0.15 |
Hazard ratios (HR) express the risk per SD change in the Doppler diastolic velocities and its ratios. SDs were 3.7 cm/s and 2.10 cm/s for TDI e' and a' velocities and 0.65, 0.50, and 2.17 for the e'/a', E/A and E/e' ratios, respectively. All hazard ratios were adjusted for family clusters, sex, age, body mass index, systolic blood pressure, serum cholesterol, smoking, diabetes mellitus, history of cardiac disease, and LV mass index. CI indicates confidence interval; LV, left ventricular; TDI, tissue Doppler imaging.