. 2014 Apr 29;3(3):e000789. doi: 10.1161/JAHA.114.000789

Table 6.

Baseline Echocardiographic Characteristics of Participants by Diastolic Function Group

Characteristic	Normal Function (n=594)	Impaired Relaxation (n=76)	Elevated End‐Diastolic Pressure (n=96)	Combined Dysfunction (n=27)
Transmitral E/A ratio	N	↓	N	↓
E/e' ratio	N	N	↑	↑
Conventional echocardiography
LA volume index, mL/m²	21.8±5.3	27.1±6.6	28.4±7.4^*^†	27.5±6.8^*^†
LV internal diameter, cm	5.02±0.49	5.09±0.58	5.07±0.56	4.85±0.49
Interventricular septum, cm	0.95±0.16	1.03±0.17^*	1.07±0.15^*	1.18±0.18^*^†^‡
Posterior wall, cm	0.87±0.14	0.94±0.14^*	0.97±0.13^*	1.04±0.15^*^†
LV mass index, g/m²	88.4±19.3	100.1±32.9^*	105.8±25.7^*	115.2±22.2^*^†
Ejection fraction, %	63.4±6.2	61.8±9.0	64.0±7.1	64.0±6.9
Transmitral Doppler
E peak, cm/s	77.7±14.8	54.7±10.2^*	80.8±13.7^†	62.2±14.0^*^‡
A peak, cm/s	59.2±13.9	76.8±12.4^*	82.3±15.5^*	95.4±16.9^*^†^‡
E/A ratio	1.39±0.46	0.73±0.17^*	1.01±0.23^*^†	0.65±0.10^*^‡
IVRT, ms	94.6±14.6	110.1±19.3^*	105.1±16.4^*	109.5±21.5^*
Adur‐ARdur, ms	1.43 (−4.3 to 7.1)	11.4 (−2.8 to 28.5)^*	−18.5 (−37.1 to 5.7)^*†	16.2 (−17.1 to 28.5)^*^‡
Tissue Doppler^§
e' peak, cm/s	12.6±3.26	8.50±2.14^*	7.69±1.30^*	5.75±1.14^*^†^‡
a' peak, cm/s	9.80±2.06	11.9±1.90^*	10.4±1.82^†^*	11.4±1.24^*
e'/a' ratio	1.42±0.65	0.75±0.30^*	0.78±0.20^*	0.50±0.10^*
E/e' ratio	6.39±1.35	6.63±1.19	10.7±2.11^*^†	11.0±2.45^*^†

Values are mean (±SD), or median (10% to 90% percentile). Adur indicates mitral inflow A‐wave duration; ARdur, pulmonary vein reversal flow duration; IVRT, isovolumetric relaxation time; LA, left atrial; LV, left ventricle.

Significance for between‐groups differences: *P≤0.05 vs normal; ^†P≤0.05 vs impaired relaxation group; ^‡P≤0.05 vs elevated LV filling pressure group.

^§Averaged of septum, lateral, inferior, and posterior mitral annulus sites.