Table 7.
Adjusted Hazard Ratios Associated With LV Diastolic Dysfunction Versus Normal Function at Baseline
| LV Diastolic Function Group | Total N | Fatal and Nonfatal Events | |||||
|---|---|---|---|---|---|---|---|
| All Cardiovascular (n=59) | Cardiac (n=40) | ||||||
| N of Events | HR (95% CI) | P Value | N of events | HR (95% CI) | P Value | ||
| Normal | 554 | 19 | Referent | 10 | Referent | ||
| Impaired relaxation (group 1) | 76 | 12 | 1.77 (0.75 to 4.17) | 0.17 | 7 | 2.13 (0.70 to 6.47) | 0.17 |
| Elevated LV filling pressure (group 2 and 3) | 123 | 28 | 2.21 (1.01 to 4.83) | 0.042 | 23 | 4.50 (1.73 to 11.7) | 0.002 |
Hazard ratios (HR) express the risk in each group of left ventricular diastolic dysfunction at baseline compared with the risk in the subjects with normal function at baseline. All hazard ratios were adjusted for family clusters, sex, age, body mass index, systolic blood pressure, serum cholesterol, smoking, diabetes mellitus, and history of cardiac disease. CI indicates confidence interval; LV, left ventricular.