Table 2.
Demographics and Clinical Characteristics of Patients With Ischemic Cerebrovascular Disease (iCVD) vs Stroke Mimics (ie, Those Without Ischemic Cerebrovascular Disease) in the Derivation Cohort Over the Study Period of 9 Years
| iCVD (n=639) | Stroke Mimic (n=190) | P Value | |
|---|---|---|---|
| Age, y | 70.5±15.0 | 61.1±18.2 | <0.0001* |
| Gender—male | 48.4% | 42.1% | 0.130 |
| Ethnicity—Hispanic | 6.7% | 7.9% | 0.580 |
| Race—white | 88.6% | 86.8% | 0.516 |
| Medical history | |||
| Hypertension | 56.2% | 38.9% | <0.0001* |
| Diabetes mellitus | 19.1% | 15.8% | 0.302 |
| Hyperlipidemia | 24.6% | 19.5% | 0.145 |
| Coronary artery disease | 16.6% | 12.1% | 0.134 |
| Atrial fibrillation | 21.6% | 6.8% | <0.0001* |
| Heart failure | 6.9% | 2.6% | 0.029* |
| Previous stroke | 25.8% | 21.1% | 0.181 |
| Smoker | 5.3% | 7.4% | 0.289 |
| Seizure | 2.2% | 5.8% | 0.011* |
| Prior MI | 7.2% | 7.4% | 0.937 |
| Clinical presentation | |||
| NIHSS* | 7 (3 to 15) | 3 (1 to 8) | <0.0001* |
| NIHSS <14 | 25.2% | 9.6% | <0.0001* |
| Signs at presentation | |||
| Facial weakness | 66.8% | 34.2% | <0.0001* |
| Limb(s) weakness | 73.6% | 55.8% | <0.0001* |
| Speech problem | 66.4% | 52.1% | <0.0001* |
| Altered LOC | 40.7% | 42.1% | 0.727 |
| Hypertensive crisis | 22.5% | 15.8% | 0.006* |
| Medications | |||
| Antiplatelet | 41.9% | 34.2% | 0.056* |
| Anticoagulation | 9.2% | 5.3% | 0.082* |
Ext. indicates external; iCVD, ischemic cerebrovascular disease; Int., internal; LOC, level of consciousness; MI, myocardial infarction; NIHSS, National Institutes of Health Stroke Scale.
*
Continuous NIHSS; median (interquartile range).
*
Stepwise logistic regression model.