Table 2.

Model Parameters and the Range of Values Tested in Sensitivity Analyses

Model Input	Base‐Case	Range	Reference
Cost inputs (2011 CNY)
Additional cost of 90‐day clopidogrel‐aspirin regimen	1990	210 to 2388	22
One‐time hospitalization costs
Ischemic stroke, mRS 0 to 2	9866	5542 to 12519	CNSR14
Ischemic stroke, mRS 3 to 5 or 6	13081	7383 to 17114
ICH, mRS 0 to 2	11118	5932 to 13902
ICH, mRS 3 to 5 or 6	14760	7665 to 19438
MI	16793	6545 to 29434	14
Major ECH	7203	4391 to 14468
Annual posthospitalization costs
Stroke, mRS 0 to 2	6920	1728 to 8639	CNSR
Stroke, mRS 3 to 5	10932	3240 to 14255
Utility inputs
Minor or no disability (mRS 0 to 2)	0.75	0.70 to 0.90	18–19,23,25
Moderate disability (mRS 3 to 4)	0.39	0.10 to 0.50
Severe disability (mRS 5)	0.20	0.00 to 0.32
Death (mRS 6)	0	0.00 to 0.00
Utility of major ECH	0.80	0.79 to 0.84	18–20
Utility of MI	0.84	0.67 to 0.96	18–19,21
Probabilities inputs
Recurrent rate of stroke (per patient year)	0.1219	0.1163 to 0.1276	CNSR12
Among patients with recurrent stroke, proportion with:			CNSR12
ICH	0.075	0.075 to 0.146
Death	0.1933	0.1737 to 0.2128
Relative risk of stroke recurrence per life‐year	1.017	1.013 to 1.022	CNSR
Age‐specific nonstroke death rate*	0.0089 to 0.1654		13–14
Rate of major ECH	0.0038	0.0030 to 0.0048	15–16
Mortality rate of major ECH	0.06		16
Rate of MI	0.0085	0.0060 to 0.0114	15–16
Mortality rate of fatal MI	0.150	0.103 to 0.246	15,17
Discount rate inputs
Costs	0.03	0.03 to 0.08	23
Outcomes	0.03	±20%	23

All costs were converted to 2011 CNY by using the medical care component of consumer price index; to convert CNY to US dollars, divide by 6.5. CNY indicates Chinese Yuan Renminbi; mRS, modified Rankin Score; CNSR, China National Stroke Registry; MI, myocardial infarction; ECH, extracranial hemorrhage; ICH, intracerebral hemorrhage.

^*Age‐specific nonstroke death rate for only the number of 63‐year‐olds (0.0089) and 93‐year‐olds (0.1654) is presented.