Table 1.

Persistent Sodium Current in Cells Expressing WT or Mutant CaM

	Persistent Current %	n
NaV1.5+apo WT* CaM	0.3±0.2	4
NaV1.5+apo CaM‐D130G	0.2±0.1	4
NaV1.5+WT CaM	0.3±0.1	5
NaV1.5+CaM‐D130G	0.2±0.1	5
NaV1.5+CaM‐D96V	0.2±0.1	7
NaV1.5+CaM‐F142L	0.1±0.1	4
Fetal NaV1.5+apo WT CaM	0.4±0.1	6
Fetal NaV1.5+apo CaM‐D130G	0.6±0.2	7
Fetal NaV1.5+WT CaM	0.2±0.1	9
Fetal NaV1.5+CaM‐D130G	1.5±0.4*,*	13
Fetal NaV1.5+CaM‐D96V	0.4±0.1	8
Fetal NaV1.5+CaM‐F142L	0.6±0.5	8

CaM indicates calmodulin; WT, wild type.

^*apo WT CaM is Apocalmodulin (apo WT CaM is Ca²⁺‐free CaM; WT refers to the disease‐associated sites identified in the probands²).

^*P<0.05 compared to fetal Na_V1.5+WT CaM.

^*P<0.05 compared to fetal Na_V1.5+WT CaM with 10 μmol/L KN‐93.

Data compared using Kruskal‐Wallis 1‐way ANOVA and Dunn's Test.