Table 5.

Temporal Trend in Primary Outcome (Major Adverse Events) in Patients With Peripartum Cardiomyopathy

MAE	Overall	2004	2005	2006	2007	2008	2009	2010	2011	Odds Ratio Per Year*
%	13.5	11.7	14.0	12.5	11.6	14.9	15.4	12.6	15.1	—
Unadjusted OR	—	Ref.	1.23 (1.07 to 1.41)	1.08 (0.94 to 1.24)	1.00 (0.87 to 1.14)	1.32 (1.16 to 1.51)	1.38 (1.21 to 1.57)	1.09 (0.95 to 1.24)	1.35 (1.18 to 1.54)	1.03 (1.02 to 1.05)
Adjusted OR	—	Ref.	1.01 (0.86 to 1.20)	0.89 (0.75 to 1.06)	0.81 (0.69 to 0.95)	1.06 (0.91 to 1.24)	0.94 (0.80 to 1.09)	0.82 (0.70 to 0.95)	0.97 (0.83 to 1.12)	0.99 (0.98 to 1.01)

Percentages indicate weighted results. Numbers in parenthesis represent 95% confidence interval (CI). MAE indicates major adverse events; OR, odds ratio.

^*Unadjusted and adjusted odds ratios per year and P values for trend were determined using logistic regression models evaluating calendar year as a continuous variable.