Spectrum of SChLAP1 expression in benign prostatic glands, clinically localized prostate cancer, and lethal mCRPC by ISH. SChLAP1 expression in (A) benign prostatic glands, (B) low- and (C) high-GS clinically localized prostate cancer, and (D) lethal mCRPC. SChLAP1 expression varies from negative to low in benign prostatic glands and low-grade, clinically localized prostate cancers to high expression in a subset of high-grade, clinically localized prostate cancers and lethal mCRPC. Magnification, × 100. Inset in (A), (B), (C), and (D) = magnification, × 400.