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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Comments Mod Chem A Comments Inorg Chem. 2014 May;34(3-4):114–123. doi: 10.1080/02603594.2014.890099

Figure 5.

Figure 5

Inhibitory effects of [Rh(DPAE)2chrysi]3+ (bottom, left) and [Rh(PrDPA)2chrysi]3+ (bottom, center) on cellular proliferation in MMR-deficient HCT116O (red) and MMR-proficient HCT116N (green) cells as a function of BrdU incorporation during DNA synthesis (adapted from reference 35). Percent BrdU incorporation is normalized to that of untreated cells. (Bottom, right) Subcellular localization of [Rh(DPAE)2chrysi]3+ (black) and [Rh(PrDPA)2chrysi]3+ (hashed). Mitochondrial rhodium content (left axis) has been normalized to mitochondrial protein content, and nuclear rhodium content (right axis) is expressed as the percentage of cellular rhodium in the nucleus.