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. Author manuscript; available in PMC: 2015 Jan 28.
Published in final edited form as: J Neurovirol. 2004 Jun;10(3):141–151. doi: 10.1080/13550280490441103

Figure 5.

Figure 5

Effects of Tat1-72 and gp120 on caspase-3 activation in striatal neurons at 4 h, 24 h, and 72 h following continuous exposure in vitro. Both Tat (100 nM) and gp120 (500 pM) significantly increased caspase-3 activity at 4 h, 24 h, and 72 h. Caspase-3 activity was expressed as fluorescence units per µg of cytosolic protein and averaged from triplicate determinations each from at least n = 4 separate experiments. Mean caspase-3 activity in vehicle-treated (control) cultures was 69.71 units/µg protein (*P < 0.015 versus vehicle-treated cultures; ANOVA, post hoc Duncan’s test; bP< 0.05 versus vehicle-treated or Tat-treated cultures; ANOVA, post hoc Duncan’s test).

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