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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Reprod Toxicol. 2014 Jan 18;45:59–70. doi: 10.1016/j.reprotox.2014.01.006

Figure 2.

Figure 2

Overview of the study design. Beginning at approximately postnatal day 45 (P45), mice were administered 1 mg/kg AgNPs through tail vein injection 5 times, once every 3 days (corresponding to days 0, 3, 6, 9, and 12 post-exposure). Per post-exposure time point assessed (15, 60, and 120 days post-initial exposure), six control and six treated mice were used for isolation of blood, testes, and sperm. Meanwhile, a separate group of six control and six treated mice were used for breeding assessment. The numbers on the bottom right corner of the black boxes indicate a group of mice.