Serum and intratesticular levels of testosterone in AgNP-treated animals.
The graphs show serum luteinizing hormone (LH) (Panel A), follicle stimulating hormone (FSH) (Panel B), serum testosterone (Panel C) levels, intratesticular testosterone (Panel D), and serum IGF1 (Panel E) levels at the indicated time points post-initial exposure. Serum LH, FSH, and IGF1 were not significantly altered by AgNP treatment; however, serum and intratesticular testosterone were significantly elevated at 15 days post-initial exposure. Statistical analysis was performed using one-way ANOVA (A-D) or Student’s t-test (E). n=12; **P<0.05.