Figure 5. Occluded conformation of LbSemiSWEET.

(a) Crystal structure of L. biflexa SemiSWEET (PDB 4QNC), showing the slight bending of TM2. The 3TM repeats are coloured as in Fig. 1c. The residues constituting the gates are shown as stick models. (b) Close-up view of the extracellular gate of L. biflexa SemiSWEET. The hydrogen-bonding and salt bridge interactions are depicted as black dotted lines. (c) Close-up view of the intracellular gate of L. biflexa SemiSWEET.