Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jan 19;6:6020. doi: 10.1038/ncomms7020

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015, Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(a) Schematic showing the strategy and principle of induced VEGFR2 ablation in Apln⁺ cells. Tam., tamoxifen treatment. (b) Picture of tumours from Apln-CreER;VEGFR2^fl/fl and littermate controls Apln-CreER;VEGFR2^fl/+ mice. (c) Quantification of tumour volume (length × width²/2 (mm³)) at different times following implantation. Student’s t-test was used to analyse differences and values are shown as means±s.e.m.; *P<0.05; n=6–8 for each time point. (d) Whole mount view of RFP⁺ tumours. (e) Vessel detection by PECAM staining and quantification of vessel number in different groups. Student’s t-test was used to analyse differences and values are shown as means±s.e.m.; *P<0.05; n=6. Scale bars, 1 mm (d); 0.5 mm (e).