Table 3.
Neuropsychological test scores at baseline—all participants
| AN-P |
HC |
Paired |
|||||
|---|---|---|---|---|---|---|---|
| Mean | SD | mean | SD | Mean diff | p-value | ES | |
| WISC-III/WAIS-III | |||||||
| Full Scale IQ (FSIQ) | 101.1 | 16 | 102 | 13.4 | −0.8 | 0.695 | −0.058 |
| Verbal IQ (VIQ) | 104.6 | 16.9 | 103 | 13.3 | 1.7 | 0.444 | 0.114 |
| Performance IQ (PIQ) | 96.3 | 14.4 | 100.3 | 13.3 | −4 | 0.051 | −0.284 |
| Difference (VIQ − PIQ) | 8.3 | 14.9 | 2.7 | 14 | 5.7 | 0.007 | 0.393 |
| Verbal Comprehension Index (VCI) | 106.2 | 16.7 | 103.6 | 12.7 | 2.7 | 0.226 | 0.18 |
| Working Memory Index (WMI) | 98.2 | 15.5 | 97.9 | 14 | 0.2 | 0.914 | 0.016 |
| Perceptual organization Index (POI) | 93 | 14.6 | 98.3 | 13.5 | −5.4 | 0.009 | −0.381 |
| Processing speed Index (PSI) | 108.2 | 17.6 | 108.7 | 19.2 | −0.2 | 0.945 | −0.01 |
| Difference (VCI – POI) | 13.2 | 16.2 | 5.4 | 15 | 8.1 | <0.001 | 0.517 |
| RCFT | |||||||
| copy | 33.5 | 2.4 | 32.3 | 2.7 | 1.2 | 0.003 | 0.45 |
| Time to copy | 201.3 | 86.6 | 191.4 | 68.2 | 9.5 | 0.397 | 0.127 |
| Immediate recall | 21.5 | 6.4 | 21.4 | 5.4 | 0.2 | 0.798 | 0.037 |
| Delayed recall | 21.5 | 6.5 | 21.2 | 5 | 0.3 | 0.721 | 0.049 |
| Trail making | |||||||
| A | 32.1 | 13 | 27.6 | 10.6 | 0.8 | 0.505 | 0.066 |
| B | 69.2 | 31.3 | 63.4 | 25.5 | 0 | 0.814 | 0 |
| Difference (B − A) | 37.1 | 25.7 | 35.8 | 21.7 | −0.8 | 0.594 | −0.036 |
| TOMAL-2 | |||||||
| Memory for Stories | 28.3 | 10.1 | 31.6 | 7.8 | −3.7 | 0.009 | −0.402 |
| Memory for Stories—delayed recall | 24.3 | 10.6 | 26.8 | 8 | −2.7 | 0.077 | −0.287 |
| Word Selective Reminding | 60.3 | 9.6 | 61.4 | 5.6 | −0.9 | 0.349 | −0.142 |
| Word Selective Reminding—delayed recall | 10.6 | 1.8 | 10.5 | 1.5 | 0.1 | 0.547 | 0.098 |
| CANTAB | |||||||
| IED stages completed | 8.5824 | 1.3087 | 8.5745 | 0.7827 | 0 | 0.375 | 0.135 |
| IED total errors adjusted | 23.5714 | 31.544 | 24.9362 | 19.7619 | −1.0659 | 0.369 | −0.13 |
| IED EDS errrors | 7.1429 | 8.4716 | 9.9468 | 10.4154 | −2.6923 | 0.097 | −0.256 |
| PRM number correct | 21.5889 | 2.398 | 21.6383 | 1.6188 | −0.1222 | 0.892 | 0.02 |
| SRM number correct | 17.0333 | 1.9282 | 17.4468 | 1.8527 | −0.4444 | 0.127 | −0.235 |
| RTI five-choice movement time | 382.62 | 103.03 | 331.92 | 75.86 | 57.11 | <0.001 | 0.633 |
| RTI five-choice reaction time | 353.92 | 143.39 | 333.97 | 43.59 | −3.31 | 0.678 | −0.066 |
| RTI simple movement time | 395.39 | 129.61 | 356.02 | 114.07 | 43.7 | 0.038 | 0.354 |
| RTI simple reaction time | 325 | 88.99 | 309.29 | 40.76 | −6.86 | 0.418 | −0.143 |
| RVP A | 0.8737 | 0.0472 | 0.8696 | 0.0507 | 0.0036 | 0.602 | 0.074 |
| SOC problems solved in minimum moves | 8.2584 | 1.9973 | 8.7447 | 1.8076 | −0.4831 | 0.069 | −0.254 |
| SOC mean initial thinking time 5 | 5642.96 | 4716.04 | 5933.35 | 5299.95 | −425.01 | 0.726 | −0.053 |
| SOC mean moves 5 | 7.0534 | 1.7236 | 6.7029 | 1.2147 | 0.3519 | 0.132 | 0.238 |
| SOC mean subsequent thinking time 5 | 827.75 | 1152.29 | 875.68 | 905.92 | −127.47 | 0.332 | −0.145 |
| SSP span length | 6.7528 | 1.5542 | 6.9574 | 1.1996 | −0.2135 | 0.312 | −0.152 |
| SWM strategy | 30.9659 | 5.1135 | 31 | 5.3581 | 0.1136 | 0.875 | 0.022 |
| SWM total errors | 180.568 | 172.643 | 182.979 | 149.032 | 0.1477 | 0.946 | 0.009 |
This table provides a complete overview of the study results of cognitive measures with mean and standard deviation (SD) for the patients with anorexia nervosa and HC as well as paired mean difference (mean diff), p-values and effect size (ES).
RCFT, Rey Osterreith Complex Figure Test; TOMAL-2, Test of Memory and Learning—Second Edition; CANTAB, Cambridge Neuropsychological Test Automated Battery; IED, Intra-Extra Dimensional Set Shift; EDS, Extra-Dimensional Stage; PRM, Pattern Recognition Memory; SRM, Spatial Recognition Memory; RTI, Simple and Choice Reaction Time; RVP, Rapid Visual Information Processing; SOC, Stockings of Cambridge; SSP, Spatial Span; SWM, Spatial Working Memory; IQ, Intelligence Quotient.