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. 2015 Jan 26;156(2):222–230. doi: 10.1097/01.j.pain.0000460302.56325.0c

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© 2015 International Association for the Study of Pain

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Statistical comparison of the electroencephalography traces of 1- to 2-month-olds (blue) and 12-month-olds (red) for the first (left) and second (right) waveforms. For each waveform, traces were aligned between groups (without affecting within-group alignment). Independent samples t tests assessed whether the distribution of amplitudes at each time point in a region of interest centered on the waveform (150-600 milliseconds for the first waveform; 550-1100 milliseconds for the second waveform) differed between the 2 groups. The aligned group averages (±SD) are shown, with statistically significant differences highlighted in gray.