Table 6. Comparison of baseline clinical characteristics between survivors and non-survivors who had a normal serum Cr.
| Parameters | survivor (n = 37) | Non-survivor (n = 21) | P value (Cox univariate) | P value (Cox multivariate) | RR (95% CI) |
|---|---|---|---|---|---|
| Age (yr) | 42 (17–60) | 43 (34–75) | 0.059 | ||
| Male, n (%) | 36 (97.3%) | 18 (85.7%) | 0.094 | ||
| Alanine aminotransferase (IU/L) | 149 (25–1499) | 102 (18–2495) | 0.430 | ||
| Albumin (g/L) | 30 (19–45) | 28 (23–38) | 0.473 | ||
| Blood Urea Nitrogen (mmol/L) | 3.9 (1.9–7.3) | 4.0 (2.2–8.1) | 0.497 | ||
| Sodium (mmol/L) | 136 (126–144) | 133 (122–143) | 0.184 | ||
| Total bilirubin (mg/ml) | 16.7 (10.1–30.9) | 24.4 (12.9–41.8) | <0.001 | 0.01 | 1.07 (1.02–1.12) |
| Creatinine (mg/ml) | 1.0 (0.7–1.2) | 1.0 (0.7–1.2) | 0.779 | ||
| International normalized ratio (INR) | 1.8 (1.5–2.7) | 2.1 (1.5–3.8) | 0.010 | ||
| White Blood Cells (109/L) | 6.1 (1.7–15.4) | 6.8 (2.6–17.5) | 0.219 | ||
| HBV DNA (Log10 copies/ml) | 4.9 (1.8–8.1) | 2.9 (1.6–9.5) | 0.169 | ||
| Cirrhosis, n (%) | 23 (62.2%) | 13 (61.9%) | 0.732 | ||
| CTP scoring | 11 (9–13) | 12 (9–13) | 0.041 | ||
| MELD scoring | 23 (18–30) | 27 (21–37) | < 0.001 | ||
| MELD-Na scoring | 24 (4–37) | 31 (14–48) | < 0.001 | ||
| Cystatin C (mg/L) | 1.34 (0.81–1.86) | 1.78 (1.16–3.04) | < 0.001 | 0.006 | 4.92 (1.96–12.35) |
| Ascites, n (%) | 28 (75.7%) | 16 (76.2%) | 0.965 | ||
| Spontaneous bacterial peritonitis, n (%) | 7 (18.9%) | 5 (23.8%) | 0.659 | ||
| Hepatic encephalopathy (I–II), n (%) | 5 (13.5%) | 5 (23.8%) | 0.318 |
All data were present as median (min-max) or number (%).