Table 5. Association of Chlorpyrifos and Diazinon Detection in Plasma and PON1 Activities on Maternal Urinary Diethyl Phosphate Metabolites (n=206).
| Diethyl Phosphate Metabolites (nmol/L) | ||
|---|---|---|
| Change in Urinary Diethyl Phosphates (95% Confidence Interval) | ||
| Diazinon | ||
| Arylesterase | ||
| Diazinon(Nondetect vs Detectable) | 0.61(0.13,1.09) | |
| Maternal Arylesterase Activity | 0.05(-0.05,0.14) | |
| Diazinon x Arylesterase Activity | -0.20(-0.35,-0.05) | |
| Chlorpyrifos-oxonase | ||
| Diazinon(Nondetect vs Detectable) | 0.002(-0.15,0.16) | |
| Maternal Chlorpyrifos-oxonase Activity | 0.003(-0.07,0.08) | |
| Paraoxonase | ||
| Diazinon(Nondetect vs Detectable) | -0.002(-0.16,0.15) | |
| Maternal Paraoxonase Activity | 0.07(-0.010,0.14) | |
| Chlorpyrifos | ||
| Arylesterase | ||
| Chlorpyrifos(Nondetect vs Detectable) | 0.46(-0.14,1.06) | |
| Maternal Arylesterase Activity | 0.09(-0.08,0.27) | |
| Chlorpyrifos x Arylesterase Activity | -0.15(-0.35,0.04) | |
| Chlorpyrifos-oxonase | ||
| Chlorpyrifos(Nondetect vs Detectable) | 0.01(-0.16,0.17) | |
| Maternal Chlorpyrifos-oxonase Activity | 0.004(-0.07,0.08) | |
| Paraoxonase | ||
| Chlorpyrifos (Nondetect vs Detectable) | -0.003(-0.17,0.16) | |
| Maternal Paraoxonase Activity | 0.07(-0.01,0.14) | |
Change in urinary diethyl phosphates for PON1 Activity and for interaction terms are expressed per standard deviation change in PON1 Activity. The standard deviations for maternal arylesterase. chlorpyrifos-oxonase, and paraoxonase activities were 44.5 U/mL, 2235.4 U/L, and 621.6 U/L, respectively.