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. Author manuscript; available in PMC: 2015 Jan 28.
Published in final edited form as: Hypertension. 2012 Sep 10;60(5):1226–1233. doi: 10.1161/HYPERTENSIONAHA.112.197871

Figure 2.

Figure 2

ETS-1 blockade reduces matrix expansion in angiotensin II (Ang II)–infused mice. A, Representative photomicrographs of sections stained with periodic acid Schiff to assess extracellular matrix (pink stain). B, Quantitative analysis of glomerular matrix expansion from mice infused with Ang II for 4 weeks with and without concomitant infusion of ETS-1 dominant-negative (ETS-1 DN) or ETS-1 mutant (ETS-1-MU) peptide. ETS-1 DN inhibited the Ang II–induced mesangial expansion (n=6 per group; *P<0.05 vs control; #P<0.05 vs Ang II).