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. 2015 Jan 20;79(2):222–240. doi: 10.1111/bcp.12441

Table 4.

Reported duration of drug-induced CYP2D6 inhibition after the last dose of the phenoconverting medication

Co-medication Duration of phenoconversion after the last dose of inhibitor References
Quinidine At least 3 days 14
21 days 53
Fluoxetine >2 weeks 27
Fluoxetine 63.2 ± 5.6 days 145
Paroxetine 20.3 ± 6.4 days
Sertraline 25.0 ± 11.0 days
Terbinafine >4 weeks 146
Paroxetine 4 weeks after 6 weeks of treatment 147
6 weeks after 18 weeks of treatment