. Author manuscript; available in PMC: 2015 Jan 28.

Published in final edited form as: Am J Crit Care. 2013 Sep;22(5):e62–e69. doi: 10.4037/ajcc2013835

Table 2.

Associations between evening shift and medication dosages

Main results	Relative risk (95% credible interval)
Main results	Fentanyl^a (n = 159)^b	Lorazepam^a (n = 148)^b	Haloperidol^a (n = 91)^b
Evening shift (4 pm-midnight)^c	1.06 (0.93, 1.22)	1.55 (1.29, 1.85)^d	1.75 (1.14, 2.68)^d
Linear trend over shifts	1.07 (1.05, 1.09)^d	1.02 (0.99, 1.05)	1.41 (1.32, 1.52)^d

Each drug model included adjustment for age, score on Acute Physiology and Chronic Health Evaluation II, death in the intensive care unit, dementia (score on short form of the Informant Questionnaire on Cognitive Decline in the Elderly >3.3), length of stay <5 days, mechanical ventilation, sex, race, and weight in pounds.

Number of persons taking drug who survived at least 3 days in the intensive care unit.

Comparison of mean drug dose given on evening shift relative to mean doses on day and night shifts combined.

Statistical significance from 95% credible interval exclusive of zero.