. Author manuscript; available in PMC: 2015 Nov 1.

Published in final edited form as: J Sex Med. 2014 Aug 22;11(11):2744–2755. doi: 10.1111/jsm.12665

Table 3. Adjusted Associations Between Total Number of Chronic Conditions & Sexual Function Outcomes.

	Sexual Function Outcomes Assessed in All Participants (N=1997)
	Low Sexual Desire^α OR (CI)	<Monthly Sexual Activity^β OR (CI)		Low Sexual Satisfaction^γ OR (CI)
Adjusted for age, race/ethnicity, and partner status only	1.11 (1.05 - 1.17)^*	1.11 (1.05 - 1.17)^*		1.10 (1.04 - 1.16)^*
Additionally adjusted for medication use^, body mass index, menopausal status, pelvic surgery, and smoking/alcohol use^*	1.13 (1.06 – 1.21)^*	1.05 (0.98 – 1.13)^*		1.13 (1.05 – 1.22)^*
Additionally adjusted for SF-12 physical 8and mental function scores	1.10 (1.03 – 1.18)^*	1.04 (0.96 – 1.12)^*		1.10 (1.03 – 1.19)^*
	Sexual Problems Assessed in Sexually Active Participants Only (N=1193)
	Arousal Difficulty^δ OR (CI)	Lubrication Difficulty^ε OR (CI)	Orgasm Difficulty^ζ OR (CI)	Pain with Intercourse^η OR (CI)
Adjusted for age, race/ethnicity, and partner status only	1.13 (1.05–1.23)^*	1.14 (1.06–1.22)^*	1.16 (1.07–1.25)^*	1.10 (1.01 –1.20)^*
Additionally adjusted for medication use^, body mass index, menopausal status, pelvic surgery, and smoking/alcohol use^*	1.21 (1.09–1.35)^*	1.26 (1.14–1.39)^*	1.28 (1.15–1.42)^*	1.31 (1.16–1.49)^*
Additionally adjusted for SF-12 physical 8and mental function scores	1.19 (1.07–1.33)^*	1.22 (1.10–1.35)^*	1.24 (1.12–1.38)^*	1.28 (1.13–1.45)^*

Odds ratio reflects change in odds per each additional chronic condition.

^α

Participants were considered to have low to no sexual desire if they described their “sexual desire or interest” as low, very low, or none.

^β

Participants were considered to have less than monthly sexual activity if they reported no sexual activity or less than monthly sexual activity in the past three months.

^γ

Participants were considered to have low overall sexual satisfaction if they indicated that they were less than “moderately” satisfied.

^δ

Participants were considered to difficulty with arousal if they reported their level of sexual arousal during sexual activity was low, very low, or none.

^ε

Participants were considered to have difficulty with lubrication if they reported it was difficult, very difficult, extremely difficult, or impossible to become lubricated during sexual activity.

^ζ

Participants were considered to have difficulty with orgasm if they reported it was difficult, very difficult, extremely difficult, or impossible to reach orgasm during sexual stimulation or intercourse

^η

Participants were considered to have pain or discomfort with intercourse if they reported their level of discomfort or pain during or after vaginal penetration was moderate, high, or very high.

^**

Medication use covariate consists of medication types utilized in the past two years. See Appendix C for details.

^***

Additional covariates included BMI, menopausal status, any pelvic surgery, current smoking, and >5 alcoholic drinks/week.