FIG 7.

Intermediary metabolism and glycolysis/gluconeogenesis of “Ca. Methanoplasma termitum” and other Methanomassiliicoccales. Black arrows indicate reactions whose enzymes are encoded by all genomes. Blue-green arrows indicate that the enzymes are not present in “Ca. Methanoplasma termitum” but are present in the genomes indicated by the colored dots. Purple arrows indicate link points to amino acid and nucleic acid biosynthesis. Gray arrows indicate important enzymes not encoded by any of the four genomes. *, “Ca. Methanomethylophilus alvus” has gpmA instead of apgM; #, acnA was not found in Mmc. luminyensis.