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. 2015 Jan 23;17(1):89–100. doi: 10.1016/j.neo.2014.11.005

Figure 7.

Figure 7

Inverse correlation between the presence of granulosa cells and epithelial lesions in Wv/Wv ovaries. Representative examples of tissue sections stained with the granulosa cell marker inhibin-alpha (A, C, E) and epithelial marker CK8 (B, D, F) in adjacent sections of ovarian tissues from 3-month-old wild-type (A, B), Wv/Wv (C, D), and Wv/Wv; Trp53 (−/−) (E, F) mice. An arrow indicates the single layer of CK8-positive ovarian surface epithelial cells (B). To illustrate the inverse correlation between the presence of granulosa cells and epithelial cells, arrowheads indicate that, in an area which is positive for inhibin-alpha (C), CK8 staining is absent in the adjacent section (D).