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. 2015 Jan 20;10:749–763. doi: 10.2147/IJN.S62837

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© 2015 Wang et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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T2 relaxivity coefficient (r₂) stability test of SPION@dSiO₂.

Notes: (A) Photograph of SPION@dSiO₂ aqueous solutions with different Fe concentrations, from 0 to 3.9 mmol/L. T2-MR images of SPION@dSiO₂ (B) in deionized water, obtained by using a 3.0 T clinical MR imaging instrument. (C) Inverse transverse relaxation times (1/T2) versus Fe concentration. The slope indicates that the T2 relaxivity coefficient (r₂) =110.57 mM⁻¹·s⁻¹.

Abbreviations: SPION, superparamagnetic iron oxide nanoparticles; MR, magnetic resonance.