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. 2015 Jan 20;10:749–763. doi: 10.2147/IJN.S62837

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© 2015 Wang et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Biodistribution analysis.

Notes: The MKN45 tumor uptake of 800ZW–SPION@dSiO₂ after 48 hours pi was found to be significantly lower than that of 800ZW–SPION@dSiO₂–YY146 at those time points examined, indicating that YY146 conjugation was the controlling factor for enhanced tumor uptake of 800ZW–SPION@dSiO₂–YY146 (P<0.05).

Abbreviations: SPION, superparamagnetic iron oxide nanoparticles; pi, postinjection; NIRF, near infra-red fluorescence.