Figure 8.

MR imaging.

Notes: A series of pictures showed T2-weighted MR images acquired at the defined time points on the 11.7 T system, where (A) 800ZW–SPION@dSiO₂–YY146 appeared as discrete, punctuated, negative contrast regions. A significant decrease in image contrast occurred between the time points 24 and 48 hours followed by a gradual decrease thereafter; (B) 800ZW–SPION@dSiO₂, as the image arrows were shown, it was difficult to find the change among prescanning and three time points. Tumors are indicated by white arrows.

Abbreviations: MR, magnetic resonance; SPION, superparamagnetic iron oxide nanoparticles.