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Ex vivo imaging of the three groups.
Notes: Prominent NIRF signal from the tumor, liver, kidney, and spleen biodistribution indicated significant uptake of (A) white light photograph, (B) 800ZW–SPION@dSiO2–YY146, (C) 800ZW–SPION@dSiO2 with a blocking dose of YY146, (D) 800ZW–SPION@dSiO2 in these three organs at 48 hours pi, which corroborated the in vivo findings.
Abbreviations: NIRF, near infra-red fluorescence; SPION, superparamagnetic iron oxide nanoparticles; pi, postinjection.
