Table 1.

Age, sex, and previous history (%, unless otherwise stated)

	2001		2007		2001+2007		P*	P**
	Cons (n=706)	Inv (n=97)	Cons (n=463)	Inv (n=147)	Cons (n=1,169)	Inv (n=244)
Age (mean ± SD; years)	84±5	79±3	85±5	81±4	84±5	80±4	<0.0001	0.33
Women	53	40	57	46	55	43	0.053	0.83
Past medical history
Risk factors for AMI
Hypertension	54	59	57a	59a	55a	59a	0.48	0.71
Diabetes	21	20	28	24	24	22	0.18	0.69
Smoking at time of arrival	10c	14	7	11a	9b	12a	0.64	0.89
Previous heart disease
Acute myocardial infarction	44	31a	44	36	44	34	0.03	0.59
Angina pectoris	48	38	31a	32a	41a	35a	0.34	0.19
Cardiac arrest	1a	2	0	0a	<1	< 1	1.00	–
CABG	8	6	12	14a	10	11	0.41	0.37
PCI	3	8	7	19a	4	14	<0.0001	0.76
Congestive heart failure	44	16	36	11	41	13	<0.0001	0.69
Atrial fibrillation	29	8	27	20a	28	15a	0.001	0.003
Other vascular disease
Peripheral vascular disease	14a	20	13	9	14	13	0.44	0.04
Cerebrovascular disease	25	12	24	13	24	13	0.0002	0.77
Other disease
COPD	12	10	13	10	12	10	0.03	0.67
Connective tissue disease	3	0	0	0	2	0	0.03	–
Non-metastatic tumor	11a	7	6	4	9	5	0.09	0.82
Metastatic tumor	6a	3	12	6	9	5	0.08	0.97
Renal disease	9a	8	13	7	9	7	0.08	0.27
Treated at hospital with PCI facilities	48	75	55	56	51	64	0.003	0.0001

Notes:

^*For difference between conservative and invasive treated groups (age adjusted);

^**for time period by treatment interaction;

^a1%–5% missing;

^b5%–10% missing;

^c10%–25% missing.

Abbreviations: Cons, conservative; Inv, invasive; SD, standard deviation; CABG, coronary artery bypass graft; PCI, percutaneous coronary intervention; COPD, chronic obstructive pulmonary disease; AMI, acute myocardial infarction.