Table 3.
2001
|
2007
|
2001+2007
|
P* | P** | ||||
---|---|---|---|---|---|---|---|---|
Cons (n=706) | Inv (n=97) | Cons (n=463) | Inv (n=147) | Cons (n=1,169) | Inv (n=244) | |||
Thrombolysis | 4 | 16 | < 1 | 0 | 3 | 7 | 0.04 | 0.18 |
Procedures and treatment | ||||||||
Echocardiography | 31 | 82 | 25 | 70 | 29 | 75 | <0.0001 | 0.29 |
Exercise bicycle test | 6 | 20a | 2 | 2a | 4 | 9a | 0.61 | 0.08 |
PCI | 0 | 42 | 0 | 75 | 0 | 62 | – | – |
Primary | 0 | 33a | 0 | 65 | 0 | 52 | – | – |
Rescue | 0 | 7a | 0 | 0 | 0 | 3 | – | – |
Elective | 0 | 1a | 0 | 10 | 0 | 6 | – | – |
CABG | <1 | 27 | < 1 | 7 | < 1 | 15 | <0.0001 | 0.21 |
Events | ||||||||
Recurrent AMI | 3 | 6 | 2 | 4 | 2 | 5 | 0.01 | 0.94 |
Pulmonary embolism | <1a | 0 | 2 | 0 | 1 | 0 | 0.07 | 1.00 |
Pneumonia | 12a | 6 | 9 | 1 | 10a | 3 | 0.0005 | 0.13 |
Stroke | 6a | 4 | 3 | < 1 | 5 | 2 | 0.11 | 0.22 |
Deep vein thrombosis | <1a | 1 | < 1 | 0 | < 1 | < 1 | 1.00 | 0.75 |
Acute renal failure | 4a | 1 | 2 | < 1 | 4 | < 1 | 0.055 | 0.91 |
Hemorrhage requiring transfusion | 4a | 0 | 6 | 1 | 5 | < 1 | 0.01 | 0.22 |
Hypotension | 14a | 5 | 16 | 18 | 15 | 13 | 0.35 | 0.02 |
Pericarditis | 0a | 1 | 0 | < 1 | 0 | < 1 | 0.046 | 1.00 |
Cardiogenic shock | 3a | 3 | 2 | 3 | 2 | 3 | 0.87 | 0.50 |
Congestive heart failure | 54 | 29 | 19 | 13 | 40 | 19 | <0.0001 | 0.11 |
Death | 20 | 6 | 20 | 10 | 20 | 9 | 0.0003 | 0.31 |
Notes:
for difference between conservative and invasive treated groups (age adjusted);
for time period by treatment interaction;
1%–5% missing.
Abbreviations: Cons, conservative; Inv, invasive; CABG, coronary artery bypass graft; PCI, percutaneous coronary intervention; AMI, acute myocardial infarction.