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Observed (obs.) and predicted (pre.) dissolution release profiles (Diss) for glyburide at dynamic pH changes (6.0, 6.5, 7.0, 7.5, and 5.0) using USP apparatus II at 37°C in 900 ml at 75 rpm in the following media: USP simulated intestinal fluid (USP-SIF), blank fasted state simulated intestinal fluid (BFaSSIF), low quality fasted state simulated intestinal fluid (LQ-FaSSIF), and high quality fasted state simulated intestinal fluid (HQ-FaSSIF)
