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Lipidomic profiling reveals altered phospholipid and cholesteryl esters in 12/15-LOX deficiency. Lipids were extracted from macrophages, and analyzed as described in Section “Materials and methods” (n=8, mean±S.E.). *Student's t-test, p<0.05. The overall differences between WT and 12/15-LOX data sets is significant following analysis by one-way ANOVA with a Tukey' post-hoc test, p<0.05 (except for cholesteryl esters).
