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. 2015 Jan 7;4:e02923. doi: 10.7554/eLife.02923

Table 3.

Quantitative RT-PCR of muscles from 2-month old wild-type and heterozygous Ryr1AG/+ mice fed for 4 weeks on the indicated diets

DOI: http://dx.doi.org/10.7554/eLife.02923.011

Gene 0.6% K Diet 5.2% K Diet
Ryr1+/+ Ryr1AG/+ Ryr1+/+ Ryr1AG/+
Abcc8 (SUR1)
 Vastus lateralis 1.00 ± 0.07 1.30 ± 0.21** 1.05 ± 0.30 1.51 ± 0.33*
 Tibialis anterior 1.00 ± 0.04 1.20 ± 0.17*** 1.09 ± 0.23 1.31 ± 0.27*
 Adductor magnus 1.00 ± 0.12 1.28 ± 0.22* 0.98 ± 0.23 1.61 ± 0.42*
Abcc9 (SUR2)
 Vastus lateralis 1.00 ± 0.19 0.81 ± 0.24 1.03 ± 0.20 1.09 ± 0.18
 Tibialis anterior 1.00 ± 0.23 0.86 ± 0.21 0.99 ± 0.13 1.18 ± 0.20
 Adductor magnus 1.00 ± 0.18 0.88 ± 0.19 1.01 ± 0.19 1.11 ± 0.11
Atpa1 (NKAα1)
 Vastus lateralis 1.00 ± 0.15 1.23 ± 0.21* 0.94 ± 0.32 0.18 ± 0.06***
 Tibialis anterior 1.00 ± 0.21 1.22 ± 0.13* 0.75 ± 0.39 0.23 ± 0.06***
 Adductor magnus 1.00 ± 0.26 1.25 ± 0.17* 0.93 ± 0.29 0.24 ± 0.07***
Clc1 (CLC1)
 Vastus lateralis 1.00 ± 0.09 1.05 ± 0.19 0.90 ± 0.21 0.84 ± 0.25
 Tibialis anterior 1.00 ± 0.10 1.10 ± 0.16 0.93 ± 0.11 0.82 ± 0.27
 Adductor magnus 1.00 ± 0.12 1.03 ± 0.21 0.89 ± 0.15 0.88 ± 0.17
Kcnj2 (KIR2.1)
 Vastus lateralis 1.00 ± 0.09 0.77 ± 0.12*** 1.75 ± 0.17*** 1.62 ± 0.13***
 Tibialis anterior 1.00 ± 0.17 0.68 ± 0.17*** 1.70 ± 0.26*** 1.55 ± 0.15***
 Adductor magnus 1.00 ± 0.18 0.59 ± 0.13*** 1.67 ± 0.33** 1.52 ± 0.18***
Kcnj8 (KATP6.1)
 Vastus lateralis 1.00 ± 0.20 0.56 ± 0.12*** 0.97 ± 0.20 0.97 ± 0.23
 Tibialis anterior 1.00 ± 0.13 0.74 ± 0.19*** 0.87 ± 0.11 0.91 ± 0.12
 Adductor magnus 1.00 ± 0.24 0.69 ± 0.16** 1.16 ± 0.20 1.08 ± 0.17
Kcnj11 (KATP6.2)
 Vastus lateralis 1.00 ± 0.15 0.96 ± 0.17 1.10 ± 0.13 1.42 ± 0.14***
 Tibialis anterior 1.00 ± 0.18 1.01 ± 0.16 1.05 ± 0.08 1.34 ± 0.09***
 Adductor magnus 1.00 ± 0.17 0.94 ± 0.09 1.0 9± 0.06 1.38 ± 0.21***
Prkaa1 (AMPK)
 Vastus lateralis 1.00 ± 0.14 1.23 ± 0.15** 1.11 ± 0.10 1.07 ± 0.14
 Tibialis anterior 1.00 ± 0.04 1.11 ± 0.06** 1.08 ± 0.05 1.07 ± 0.10
 Adductor magnus 1.00 ± 0.11 1.20 ± 0.11*** 1.01 ± 0.11 1.10 ± 0.06

Values normalized to GAPDH before normalization to Ryr1+/+ control on 0.6% diet. Asterisks indicates significant value * = 0.05, ** = 0.001, *** = 0.005.