Table 1. Characteristics of publications identified for the meta-analysis.
Study | Year | Country | Ethnicity | Source of Control | HWE | Sample Size (Case/Control) | Genotype Distribution (Case/Control) | Genotyping Method | ||
---|---|---|---|---|---|---|---|---|---|---|
MspI (rs4646903) | ||||||||||
Wt/Wt (TT) | Wt/Vt (CT) | Vt/Vt (CC) | ||||||||
Wang [19] | 2008 | China | Asian | PB | <0.001 | 143/153 | 62/96 | 64/40 | 17/17 | PCR-RFLP |
Chen [21] (1) | 2011 | China | Asian | PB | 0.022 | 181/350 | 80/237 | 83/94 | 18/19 | PCR-RFLP |
Wang [22] (1) | 2012 | China | Asian | PB | 0.053 | 207/236 | 89/113 | 87/91 | 31/32 | PCR-RFLP |
Ile462Val (rs1544410) | ||||||||||
Ile/Ile (AA) | Ile/Val (GA) | Val/Val (GG) | ||||||||
Wang [20] | 2008 | China | Asian | PB | 0.001 | 158/139 | 69/56 | 66/48 | 23/35 | PCR-RFLP |
Chen [21] (2) | 2011 | China | Asian | PB | <0.001 | 181/350 | 77/174 | 63/122 | 41/54 | PCR-RFLP |
Wang [22] (2) | 2012 | China | Asian | PB | 0.064 | 207/236 | 106/116 | 80/90 | 21/30 | PCR-RFLP |
Ahmad [23] | 2013 | India | Asian | PB | 0.382 | 196/250 | 53/112 | 98/106 | 45/32 | PCR-ASO |
HWE Hardy–Weinberg equilibrium, PCR-RFLP polymerase chain reaction-restriction fragment length polymorphism, PCR–allele specific oligonucleotide (PCR–ASO).