Table 4.
Multivariable analysis as a function of extrapelvic (hematologic, peritoneal, and lymphatic recurrences beyond the radiation field) disease-free survival in patients with grade 3 endometrioid, serous, and clear cell endometrial cancera.
| Variable | No. of patients | Univariable analysisHR (95% CI) | Multivariable analysisHR (95% CI) | P value |
|---|---|---|---|---|
| Lymphovascular space invasion | .04 | |||
| No | 25 | Reference | Reference | |
| Yes | 36 | 2.53 (1.05–6.10) | 2.53 (1.05–6.10) | |
| Cervical stromal invasion | ||||
| No | 47 | Reference | ||
| Yes | 14 | 1.91 (0.80–4.58) | ||
| Site of node positivity | ||||
| Pelvis only | 30 | Reference | ||
| Paraaortic ± pelvis | 31 | 2.03 (0.93–4.44) | ||
| Node positivity | ||||
| <3 | 30 | Reference | ||
| ≥3 | 30 | 1.68 (0.77–3.63) |
Abbreviation: HR, hazard ratio.
a
Only clinicopathologic variables with P < .20 on univariable analysis were considered.