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Alterations in selected pathways in head and neck squamous cell cancers. Green: Frequency of mutations. Red: frequency of amplification. Blue: Frequency of deletion. (A) Mitogenic Pathway Alterations. (B) Cell Cycle Alterations. (C) NOTCH Signaling. (D) Oxidative Stress Response. See text for more details of alterations in each pathway (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.).
