Table 2.
Frequency of selected genes recurrently mutated in 4 major sequencing studies to date.
| Gene | Stransky | Agrawala | Pickering | India ICGC |
|---|---|---|---|---|
| p53 | 62% | 47% | 66% | 62% |
| CDKN2A | 12% | 9.2% | ![]() |
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| CASP8 | 8% | ![]() |
10% | 34% |
| FAT1 | 12% | ![]() |
28% | 40% |
| NOTCH1 | 14% | 15% | 9% | 16% |
| HRAS | 5% | 4% | 9% | 12% |
| PIK3CA | 8% | 6% | 11% | ![]() |
| MLL2 | ![]() |
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| FBXW7 | ![]() |
5% | ![]() |
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Red indicates genes were not identified as significant in that study.
Did not use formal statistical testing.








