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. 2014 Jul 12;1(1):75–86. doi: 10.1016/j.gendis.2014.07.002

Table 2.

Frequency of selected genes recurrently mutated in 4 major sequencing studies to date.

Gene Stransky Agrawala Pickering India ICGC
p53 62% 47% 66% 62%
CDKN2A 12% 9.2% graphic file with name fx3.gif graphic file with name fx2.gif
CASP8 8% graphic file with name fx1.gif 10% 34%
FAT1 12% graphic file with name fx3.gif 28% 40%
NOTCH1 14% 15% 9% 16%
HRAS 5% 4% 9% 12%
PIK3CA 8% 6% 11% graphic file with name fx7.gif
MLL2 graphic file with name fx4.gif graphic file with name fx3.gif graphic file with name fx6.gif graphic file with name fx9.gif
FBXW7 graphic file with name fx5.gif 5% graphic file with name fx8.gif graphic file with name fx2.gif

Red indicates genes were not identified as significant in that study.

a

Did not use formal statistical testing.