Table 2.
Overall clinical characteristics of patients with major trauma
| Screening cohort | Validation cohorts | ||
|---|---|---|---|
| Chongqing (N = 837) | Zhejiang (N = 340) | Yunnan (N = 367) | |
| Age (yrs) | 41.1 ± 13.4 (18-65) | 42.5 ± 12.0 (19-65) | 37.6 ± 12.5 (18-65) |
| Male/female, n | 672/165 | 266/74 | 282/85 |
| Injured body regions, n (%) | |||
| Head, n | 458 (54.7) | 248 (72.9) | 225 (61.3) |
| Thorax, n | 513 (61.2) | 209 (61.5) | 186 (50.7) |
| Abdomen, n | 389 (46.4) | 118 (34.7) | 105 (28.6) |
| Extremities, n | 425 (50.8) | 179 (52.6) | 196 (53.4) |
| Number of regions injured, n (%) | |||
| One, n | 435 (52.0) | 146 (42.9) | 157 (42.8) |
| Two, n | 267 (31.9) | 129 (37.9) | 131 (35.7) |
| Three or above, n | 135 (16.1) | 65 (19.1) | 79 (21.5) |
| ISS | 22.3 ± 9.4 | 21.7 ± 7.7 | 21.3 ± 9.2 |
| ≥16, <25, n (%) | 510 (60.9) | 197 (57.9) | 228 (62.1) |
| ≥25, n (%) | 327 (39.1) | 143 (42.1) | 139 (37.9) |
| Organ dysfunction, n (%) | |||
| One, n | 268 (32.2) | 112 (32.9) | 125 (34.1) |
| Two, n | 121 (14.5) | 56 (16.5) | 51 (13.9) |
| Three or above, n | 41 (4.9) | 23 (6.8) | 35 (9.5) |
| Sepsis, n (%) | 346 (41.3) | 129 (37.9) | 130 (35.4) |
| Source of infection, % | |||
| Respiratory tract infection | 41.6 | 39.7 | 43.2 |
| Primary bloodstream infection | 21.5 | 24.1 | 19.9 |
| Urinary tract infection | 16.2 | 11.2 | 12.1 |
| Catheter-associated infection | 10.9 | 9.1 | 9.3 |
| Wound infection | 7.4 | 9.1 | 10.1 |
| Others* | 2.4 | 6.8 | 5.4 |
| Pathogens, % (positive blood cultures) | |||
| Gram-negative | 22.3 | 25.7 | 29.5 |
| Gram-positive | 17.6 | 13.2 | 12.8 |
| Fungi | 2.8 | 3.5 | 3.6 |
| Mixed Gram-negative and -positive | 5.9 | 7.5 | 8.5 |
| Negative blood cultures | 54.0 | 55.0 | 57.0 |
ISS, Injury Severity Score.