Table 3.
Clinical manifestations in patients.
| Clinical manifestation | HFE-HH (n = 16) | Non-HFE-HH iron elevation (n = 92) | P value |
|---|---|---|---|
| Arthropathy | 7/13 (53.8) | 7/44 (15.9) | 0.008 |
| Cardiopathy | 10/14 (71.4) | 23/36 (63.8) | 0.500 |
| Cirrhosis | 12/16 (75.0) | 58/92 (63.0) | 0.316 |
| Hepatocellular carcinoma | 5/16 (31.2) | 6/85 (7.06) | 0.008 |
| Skin hyperpigmentation | 4/10 (40.0) | 15/55 (27.2) | 0.331 |
| Diabetes | 9/16 (56.2) | 27/90 (30.0) | 0.040 |
| Hypogonadism | 5/13 (38.4) | 9/61 (14.7) | 0.056 |
| Osteoporosis | 8/11 (72.7) | 9/28 (32.1) | 0.026 |
| Thyroidopathy | 4/16 (25.0) | 10/88 (11.3) | 0.142 |
Data are presented as number of patients affected/total number of individuals assessed (%).
HFE HH: HFE hereditary hemochromatosis.
Non-HFE-HH iron elevation: patients with iron elevation not related to HFE-HH genotypes.