Table 8.
Multivariable Cox's Regression Analysis of the Median of Gal‐3 as Independent Predictor of CV Death Within 5 Years Adjusted for Potential Confounders in PAD Population (STUDY 3, n=309)
| B | SE | P Value | Adjusted HR | 95% CI for Adjusted HR | ||
|---|---|---|---|---|---|---|
| Lower | Upper | |||||
| Median Gal‐3 | 0.808 | 0.381 | 0.034 | 2.243 | 1.063 | 4.735 |
| Gender | 0.473 | 0.382 | 0.215 | 1.604 | 0.759 | 3.389 |
| Age | 0.037 | 0.023 | 0.113 | 1.037 | 0.991 | 1.086 |
| Current smoking | −0.519 | 0.392 | 0.185 | 0.595 | 0.276 | 1.282 |
| Diabetes mellitus | 0.306 | 0.246 | 0.213 | 1.358 | 0.839 | 2.198 |
| Lowest ankle brachial blood pressure index | −1.871 | 1.055 | 0.076 | 0.154 | 0.019 | 1.217 |
| AAA | −0.429 | 0.795 | 0.590 | 0.651 | 0.137 | 3.096 |
| Previous AMI | 0.977 | 0.395 | 0.013 | 2.656 | 1.226 | 5.756 |
| Cerebral event | 0.613 | 0.492 | 0.213 | 1.846 | 0.704 | 4.840 |
| Angina pectoris | 1.116 | 0.382 | 0.003 | 3.053 | 1.445 | 6.452 |
| Hypertension | 0.109 | 0.409 | 0.789 | 1.116 | 0.500 | 2.487 |
| hs‐CRP | 0.013 | 0.005 | 0.016 | 1.013 | 1.002 | 1.023 |
AAA indictates abdominal aortic aneurysm; AMI, acute myocardial infarction; Β, regression coefficient; Gal‐3, galectin‐3; HR, hazard ratio; hs‐CRP, high‐sensitivity C‐reactive protein; PAD, peripheral arterial disease.