Table 4.

Myocardial Perfusion Index in NIDCM Before and After Spironolactone (N=12)

	Baseline Median (IQR)	After >6 Months of Spironolactone Median (IQR)	Mean Difference (SD)	P Value*
Transmural
Rest	0.072 (0.069 to 0.079)	0.073 (0.071 to 0.080)	0.009 (0.002)	0.91
Adenosine infusion	0.13 (0.12 to 0.14)	0.14 (0.13 to 0.15)	0.008 (0.006)	0.012
P value	<0.001	<0.001
Endocardium
Rest	0.077 (0.066 to 0.094)	0.078 (0.067 to 0.096)	0.009 (0.003)	0.52
Adenosine infusion	0.13 (0.11 to 0.14)	0.15 (0.13 to 0.17)	0.019 (0.017)	<0.001
P value	<0.001	<0.001
Epicardium
Rest	0.075 (0.063 to 0.086)	0.076 (0.063 to 0.086)	0.001 (0.003)	0.092
Adenosine infusion	0.14 (0.11 to 0.16)	0.14 (0.11 to 0.16)	0.003 (0.006)	0.077
P value	<0.001	<0.001
MPRI
Transmural	1.72 (1.67 to 1.87)	1.80 (1.76 to 1.92)	0.078 (0.07)	0.005
Endocardium	1.63 (1.47 to 1.72)	1.80 (1.72 to 1.89)	0.19 (0.09)	<0.001
Epicardium	1.83 (1.67 to 1.98)	1.83 (1.69 to 2.00)	0.008 (0.02)	0.677

IQR indicates interquartile range; MPRI, myocardial perfusion reserve index; NIDCM, nonischemic dilated cardiomyopathy.

^*Wilcoxon signed‐rank test.