Figure 1.

Prospective associations of plasma phospholipid TFA with total mortality, CVD, and CHD before and after mutual adjustment. Black triangles indicate multivariate‐adjusted hazard ratios comparing adults in the top quintile category to adults in the bottom quintile category, before mutual adjustment for the 5 TFAs; red diamonds, after mutual adjustment for the 5 TFAs. Error bars represent 95% CI. All risk estimates were adjusted for age, sex, race, education, enrollment site, diabetes, hypertension, smoking, alcohol consumption, physical activity, BMI, waist circumference, dietary saturated fat, dietary monounsaturated fat, dietary fiber, plasma phospholipid EPA+DHA, plasma phospholipid linoleic acid. *P‐trend<0.05 across quintiles. BMI indicates body–mass index; CHD, coronary heart disease; CVD, cardiovascular disease; EPA+DHA, eicosapentaenoic acids plus docosahexaenoic acids; TFA, trans–fatty acid.