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Vascular smooth muscle cell function was assessed in femoral arteries from WT and angptl2 KD mice, by (A) vasoconstriction to phenylephrine (PE), and (B) dilation to sodium nitroprusside (SNP) in the absence of the endothelium. Data are mean±SEM of n=4 to 6 mice, and compared using the Mann–Whitney U test. θP<0.05 vs RD. KD indicates knockdown; RD, regular diet; WT, wild‐type.
