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. 2014 Aug 15;3(4):e001024. doi: 10.1161/JAHA.114.001024

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© 2014 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Figure 7. — ACh‐mediated relaxation in mesenteric arteries of 6‐month‐old mice fed an (A) RD, (B) HFD under no‐drug control condition and with LNNA in WT (n=6) fed an (C) RD or (D) HFD, and in KD (n=6 to 10) fed an (E) RD or (F) HFD. The z‐score method followed by the d'Agostino–Pearson omnibus test was used to test normality of data sets, after which the 2‐way ANOVA followed by the Bonferonni posttest were used. §P<0.05 vs control. ACh indicates acetylcholine; HFD, high‐fat diet; KD, knockdown; LNNA, Nω‐nitro‐l‐arginine; RD, regular diet; WT, wild‐type.