Table 2.

Baseline Characteristics Associated With Multiple Occurrences of CVD, MI, or Stroke

	HR (95% CI)	P Value
Heart rate by 10/min	1.079 (1.035 to 1.124)	0.0003
Age ≥75 years	1.461 (1.258 to 1.697)	<0.0001
Multirace	1.417 (1.081 to 1.857)	0.0115
Region: North America	1.298 (1.144 to 1.473)	<0.0001
History of hypertension	1.156 (1.012 to 1.321)	0.0323
History of diabetes mellitus	1.378 (1.228 to 1.546)	<0.0001
History of stroke	1.266 (1.023 to 1.568)	0.0302
History of myocardial infarction	1.377 (1.201 to 1.580)	<0.0001
History of peripheral arterial vascular disease	1.595 (1.359 to 1.872)	<0.0001
History of percutaneous coronary intervention	1.160 (1.012 to 1.330)	0.0334
History of coronary artery bypass grafting	1.713 (1.479 to 1.983)	<0.0001
Qualifying event: troponin or CK‐MB >upper limit of normal	1.670 (1.254 to 2.224)	0.0004
ST‐segment elevation at enrollment	1.254 (0.991 to 1.587)	0.0598
ST‐segment depression at enrollment	1.384 (1.232 to 1.556)	<0.0001
Renal insufficiency: CrCl <30 mL/min	2.459 (1.818 to 3.325)	<0.0001
Renal insufficiency: CrCl ≤30 to <60 mL/min	1.382 (1.174 to 1.627)	0.0001
Killip scale I	0.600 (0.500 to 0.722)	<0.0001
Taking thienopyridine at enrollment	1.191 (1.000 to 1.419)	0.0505
Taking statin at enrollment	1.193 (1.027 to 1.384)	0.0206

CI indicates confidence interval; CK‐MB, creatine kinase‐MB; CrCl, creatinine clearance; CVD, cardiovascular death; HR, hazard ratio; MI, myocardial infarction.